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Kenji M Fujihara Selected Research

eprenetapopt

10/2021SLC7A11 Is a Superior Determinant of APR-246 (Eprenetapopt) Response than TP53 Mutation Status.
1/2021A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death.
1/2021Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells.

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Kenji M Fujihara Research Topics

Disease

4Neoplasms (Cancer)
10/2021 - 01/2020
2Hematologic Neoplasms (Hematological Malignancy)
10/2021 - 01/2021
1Adenocarcinoma
01/2022
1Mitochondrial Diseases (Mitochondrial Disease)
01/2022
1Esophageal Neoplasms (Esophageal Cancer)
10/2021
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2021
1Cataract and cardiomyopathy
01/2021
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
01/2021
1Carcinoma (Carcinomatosis)
01/2020
1Breast Neoplasms (Breast Cancer)
01/2020
1Neurodegenerative Diseases (Neurodegenerative Disease)
11/2019

Drug/Important Bio-Agent (IBA)

4Proteins (Proteins, Gene)FDA Link
01/2022 - 11/2019
3eprenetapoptIBA
10/2021 - 01/2021
1Circulating Tumor DNAIBA
01/2022
1Amino Acid Transport Systems (Amino Acid Transporter)IBA
01/2022
1Cisplatin (Platino)FDA LinkGeneric
10/2021
12,2- bis(hydroxymethyl)- 1- azabicyclo(2,2,2,)octan- 3- oneIBA
10/2021
1Fluorouracil (Carac)FDA LinkGeneric
10/2021
1Biomarkers (Surrogate Marker)IBA
10/2021
1Asparaginase (Elspar)FDA Link
01/2021
1AsparagineIBA
01/2021
1CarbonIBA
01/2021
1Pharmaceutical PreparationsIBA
01/2021
1Serine (L-Serine)FDA Link
01/2021
1Sulfhydryl Compounds (Thiols)IBA
01/2021
1multidrug resistance-associated protein 1IBA
01/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2020
1Hormones (Hormone)IBA
01/2020

Therapy/Procedure

3Therapeutics
10/2021 - 01/2021
1Drug Therapy (Chemotherapy)
10/2021